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George Church's laboratory published its demonstration of CRISPR working in human cells in the same issue of the same journal as Feng Zhang's, in January 2013. He has spent a career at the far edge of what genetic technology can do — sequencing methods, synthetic genomes, organ transplantation from pigs — and has founded dozens of companies along the way.
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George Church is Professor of Genetics at Harvard Medical School and a core faculty member at the Wyss Institute. He contributed foundational methods to DNA sequencing, and his laboratory published RNA-guided human genome engineering via Cas9 in January 2013 alongside Zhang's report. His work spans multiplex editing for xenotransplantation — including extensive editing of pig genomes to remove endogenous retroviruses — synthetic genomics and DNA data storage. He co-founded Editas Medicine among many other companies.
Sources
- Science (Mali et al.) · 2013
RNA-guided human genome engineering via Cas9 ↗